Abstract: Multiplex roadway of large mining height has a large deformation, it is difficult to be controlled. analysis the deformation law of multiplex roadway through filed measurement, explain the action mechanism between surrounding rock deformation and grouting support opportunity, apply new grouting material and used to twice grouting support test. Results show: Multiplex roadway can be divided into ahead impacting zone、starting deformation zone、serve deformation zone 、tending to stable zone、stable zone; coordination support theory think that grouting support should be applied at deformation starting stage, apply twice grouting support before and after face; multiplex roadway’s deformation decreased more than 50% after twice grouting support.